Ah, I can't think of any level of relevance that would make me want to see ads, and in areas where I do want to see something, like recommendation systems, I've found that they are better when they are only based on the content I am currently looking at as opposed to based on some profile based on my whole history.
The popup never lets you choose to see fewer ads. It's a common misconception by lay people that you will see fewer ads if you block cookies, but that's not happening of course. So you may as well get relevant ones.