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This reminds me of an article that I saw 10-20 years ago about delivering small amounts of morphine or another opioid to the spine to stop the transmission of pain as effectively as administering medication to the whole body, using an intrathecal pump:

https://en.wikipedia.org/wiki/Intrathecal_pump

Supposedly there are few or no side effects since the dose is small and localized. Kind of a shame that it's not more broadly known or used IMHO, since I've been close with people with chronic pain whose quality of life was greatly impacted.



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