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That's the reason why drugs are tested in double-blind, randomized controlled trials.

The placebo effect is a major part of the effect of SSRI, which only improve 1 in 6-8 patients if you subtract the placebo effect [1].

The "number needed to treat" (NNT) mentioned below is the average number of patients that need to recieve the treatment for one of them to be in a better condition than if all of them had recieved a placebo.

1. https://www.cambridge.org/core/journals/psychological-medici...



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