I have some ketamine on order hoping it is as effective as they say. I’m also at an all time low, about to hit 40. This will be my second major round of depression in my 30’s. I have bipolar type 2, but even managed that condition is very dicey. I found that resentment was a major force behind the first round. Disappointment dominates this wave. I have a psychiatrist, who prescribed me lithium which was very helpful indeed, until I quit it. Therapy, just having someone check in is something valuable, but I quit that too. I’ll be clear I’m not offering advice. For me, I escaped the first round by taking a series of high dose psilocybin trips. Some were very pleasant, others were like dying and going to hell, literally. I did some very stupid and risky things while under the influence. But for me personally, it absolutely saved my life. It really works. But you’ve got to control the environment carefully and have a babysitter. That lasted nearly 2 years, now I’m again in trouble. Best I not say more. But that’s one solution I found