I think "know thyself" is far more valuable than "make thyself", because in real life, everyday terms we have far less control over what makes us happy than it seems, rationally.
But -- we also have far more freedom than many people realize. "I can't" usually conceals a confused morass that needs to be dredged out with a vengeance.
The decision might still be "I won't", but if you know why, and have some sense of how to maintain your emotional equilibrium, etc. you're still far, far ahead in the game.
I think the quote resonates with you (and many people!) because it's so easy to be locked into near-immobility by a kind of inarticulated wash of bad feelings about how other people must be judging us, and in fact most of this anxiety is unfounded and misleading.
It's incredibly valuable to take a kind of eyes-open "5 questions" approach to big decisions, to dig out the kind of thing like "so apparently I will do almost anything to avoid being criticized by men who resemble my father". And yeah, break free from the crowds (hint: this tends to actually earn you respect, not harsh judgment), work on improving yourself, etc..
But don't delude yourself into thinking that simply because there's no god, universal meaning, etc., you'll be able to just shake it off if you realize that your choices have earned you the contempt of those you love and respect.
I'm sure. In fact, I felt obligated to respond because of the unusually powerful rhetoric of that quote. As I hinted, I spent a while hampered by similar ways of thinking--whereas they are appealing, I now consider them very dangerous.
I'm afraid I'm with him. There's too much anger in this, I see that as a waste of energy. None of us is really free, I can't wake up tomorrow and decide to be an NBA player or the president. We have certain options for today, this week, this month, this year... Pick the best path forward, review it occasionally and pour all that energy into doing.