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aaaand then?


No and then.


The Universe asked me, "Guess what? I'm decaying"

I said, "Dude, you've gotta give me time to guess"


I was curious too; here's an HN link spelling it out and discussing in context of working there:

https://news.ycombinator.com/item?id=27571707


Agreed that his ethnicity is a silly topic to be discussed, but calling Christopher Columbus a "slightly" relevant guy definitely feels like a stretch.


Apparently discovering new islands isn't what it used to be.


He was a small gear in a long chain of events. If not Columbus, someone else would likely have found the New World. It was the age of (Europeans) Discovery after all, where many people were sailing the world and finding new routes and lands.


Indeed. Next thing somebody will be making a fuss about Isaac Newton.


This same logic applies to every discovery in all of human history.


Sure. This is just Great Man theory [1] in action. It's a bit absurd, once you know about it you see it everywhere.

It's especially distasteful when it's about people who 'discovered' places, because the next step was usually the subjugation or genocide of the people already living in the discovered place. But we still celebrate the explorers as heroes.

1. https://en.m.wikipedia.org/wiki/Great_man_theory


IIRC Cabot was trying to raise money for an expedition at the same time as Columbus and did reach continental America before him.


Sure. But it wasn’t someone else; it was Columbus.

If it were someone else, I’m certain we’d be talking about them instead.


Inyalowda, the more you share, the more your bowl will be plentiful

my favorite show ever, imo best sci fi show ever. Ceres station in the books/show is a really cool idea even though it's got several reasons why it couldn't actually work


That's some good Belter creole.

Here's @NASA's: https://x.com/NASA/status/1478118356309921792?t=1qK3gqdbZoJl...


amen. I've tried 3 tnf inhibitors that have not worked (and had negative side effects). Cosentyx (il 17a inhibitor) kinda scares me. I always like to keep my hopes that some better autoimmune treatments could come soon


Out of curiosity I'm curious why it scares you?

For context, I had been on Taltz before for psoriasis, and it worked very well. It seems like il17 inhibitors specifically are extremely targeted in what they affect.

In comparison, I was also on otezla at one point (tnf-a inhibitor) and it didnt work for me either, and the side effects were terrible.


It's the few instances of new onset IBD and generally the GI side effects. I'm lucky enough to have a pretty solid GI system that I don't want to risk messing with. I get very anxious with medicine, and my ankylosing spondylitis is sufficiently slow moving on MRI and tolerable enough that I prefer not to use the medicines. I had too many strange side effects whilst on Humira/Remicade such that it scares the crap out of me.


Understandable. I'll just say that for a sample size of n=1 I've seen no GI side effects with il17 blockers.

Which was not the case with otezla. But tnfa blockers - yeah those are bad times.

In any case, good luck with your treatment!


thank you and thanks for your n=1, wish you the best with your treatment as well


You had a skin fungal infection dumbass not some unknown mystery condition psoriasis they came up with


Wow, kid, you really have no clue about the world.


Someone commented above, but Jonathan Haidt "the anxious generation" is a place to start for a deeper analysis on the issue. Here is part 1 of a 3 part series of posts of his. I can't speak to the correlations and study directly, but Haidt's work is probably what you're looking for. https://www.afterbabel.com/p/the-case-for-causality-part-1 (the commenter elsewhere linked part 3 which I believe directly refutes this meta analysis)


I respectfully partially disagree. Sure, the term "rescue" is a bit over the top and evokes "Apollo 13" vibes. OTOH, Boeing has "$14.8bn in Pentagon contracts in 2022" [1]. Boeing has plane crash issues for years now across more than 1 model. And its space program just had an embarrassing failure. Given their failures, the amount of revenue they get from the US federal gov, and their level of influence over various aspects of defense funding/spending, I do not think this story should be dismissed as an overly sensational, run-of-the-mill story that does not make the news.

IMO, US citizens/taxpayers would be very justified to be pissed about the failures of a company that their tax dollars heavily fund (from the same article I referenced above, its like 37% of their revenue). The series of very public failures that affect people directly (planes) and affect their tax dollars (recent series of failures of their space program) certainly warrants outrage and coverage. that's my 2 cents

[1]: https://www.airforce-technology.com/features/boeing-pleads-g...

or

https://www.forbes.com/sites/greatspeculations/2020/01/02/ho...


Why wouldn't a congress person in this instance do the opposite? Give a show of hand for sake of TV and voters. Say they voted one way, but then vote the way they might be lobbied/influenced to? The public votes of congress people is frequently a campaign talking issue by virtue of opponents lambasting each other's vote records. How would secret ballots in congress have anything but the opposite effect of what you intend?


For what’s it’s worth, autoimmune drugs are amongst the highest grossing due to their cost. Rheumatoid arthritis, psoriasis, MS all do have a lot of study. I wouldn’t say it’s enough, but I don’t think the prevalence of me/cfs alters anything due to the high prevalence of the other diseases. Immune disorders are definitely mysterious though


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